Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 2.319
Filtrar
1.
Medicina (Kaunas) ; 60(4)2024 Apr 19.
Artículo en Inglés | MEDLINE | ID: mdl-38674303

RESUMEN

Background and Objectives. In emergency departments, chest pain is a common concern, highlighting the critical importance of distinguishing between acute coronary syndrome and other potential causes. Our research aimed to introduce and implement the HEAR score, specifically, in remote emergency outposts in Bosnia and Herzegovina. Materials and Methods. This follow-up study conducted a retrospective analysis of a prospective cohort consisting of patients who were admitted to the remote emergency medicine outposts in Canton Sarajevo and Zenica from 1 November to 31 December 2023. Results. This study comprised 103 (12.9%) patients with low-risk HEAR scores and 338 (83.8%) with high-risk HEAR scores, primarily female (221, 56.9%), with a mean age of 63.5 ± 11.2). Patients with low-risk HEAR scores were significantly younger (50.5 ± 15.6 vs. 65.9 ± 12.1), had fewer smokers (p < 0.05), and exhibited a lower incidence of cardiovascular risk factors compared to those with high-risk HEAR scores. Low-risk HEAR score for prediction of AMI had a sensitivity of 97.1% (95% CI 89.9-99.6%); specificity of 27.3% (95% CI 22.8-32.1%); PPV of 19.82% (95% CI 18.67-21.03%), and NPV of 98.08% (95% CI 92.80-99.51%). Within 30 days of the admission to the emergency department outpost, out of all 441 patients, 100 (22.7%) were diagnosed with MACE, with AMI 69 (15.6%), 3 deaths (0.7%), 6 (1.4%) had a CABG, and 22 (4.9%) underwent PCI. A low-risk HEAR score had a sensitivity of 97.0% (95% CI 91.7-99.4%) and specificity of 27.3% (95% CI 22.8-32.1%); PPV of 25.5% (95% CI 25.59-28.37%); NPV of 97.14% (95% CI 91.68-99.06%) for 30-day MACE. Conclusions. In conclusion, the outcomes of this study align with existing research, underscoring the effectiveness of the HEAR score in risk stratification for patients with chest pain. In practical terms, the implementation of the HEAR score in clinical decision-making processes holds significant promise.


Asunto(s)
Síndrome Coronario Agudo , Humanos , Bosnia y Herzegovina/epidemiología , Femenino , Masculino , Persona de Mediana Edad , Anciano , Estudios Retrospectivos , Síndrome Coronario Agudo/diagnóstico , Dolor en el Pecho/diagnóstico , Dolor en el Pecho/etiología , Estudios Prospectivos , Adulto , Estudios de Seguimiento , Medición de Riesgo/métodos , Servicio de Urgencia en Hospital/estadística & datos numéricos , Medicina de Emergencia/métodos , Infarto del Miocardio/diagnóstico
2.
BMC Vet Res ; 20(1): 117, 2024 Mar 23.
Artículo en Inglés | MEDLINE | ID: mdl-38521906

RESUMEN

BACKGROUND: In Bosnia and Herzegovina, domestic and wild carnivores represent a significant driver for the transmission and ecology of zoonotic pathogens, especially those of parasitic aetiology. Nevertheless, there is no systematic research of Trichinella species in animals that have been conducted in Bosnia and Herzegovina, even though trichinellosis is considered the most important parasitic zoonosis. The available results of the few studies carried out in Bosnia and Herzegovina are mainly related to the confirmation of parasitic larvae in the musculature of domestic pigs and wild boars or data related to trichinellosis in humans. The objective of our study was to present the findings of a comprehensive investigation into the species composition of Trichinella among 11 carnivorous species within the territory of Bosnia and Herzegovina, as follows: red fox (Vulpes vulpes), grey wolf (Canis lupus), brown bear (Ursus arctos), wildcat (Felis silvestris), pine marten (Martes martes), European badger (Meles meles), weasel (Mustela nivalis), European polecat (Mustela putorius), Eurasian lynx (Lynx lynx), but also dog (Canis lupus familiaris) and cat (Felis catus). RESULTS: In the period 2013-2023, carnivore musculature samples (n = 629), each consisting of 10 g of muscle tissue, were taken post-mortem and individually examined using the artificial digestion method. In the positive samples (n = 128), molecular genotyping and identification of parasitic larvae of Trichinella spp. were performed using a PCR-based technique up to the species/genotype level. Positive samples were used for basic PCR detection of the genus Trichinella (rrnS rt-PCR technique) and genotyping (rrnl-EVS rt-PCR technique). The Trichinella infection was documented for the first time in Bosnia and Herzegovina among red foxes, grey wolves, brown bears, dogs, badgers and Eurasian lynx, with a frequency rate of 20.3%. Additionally, the presence of T. britovi infection was newly confirmed in Bosnia and Herzegovina, marking the initial documented cases. Furthermore, both T. britovi and T. pseudospiralis infections were observed in the wildcat population, whereas T. britovi and T. spiralis infections were detected in pine martens. Consistent with previous research, our findings align particularly regarding carnivores, with data from other countries such as Germany, Finland, Romania, Poland and Spain, where T. britovi exhibits a wider distribution (62.5-100%) compared to T. spiralis (0.0-37.5%). T. britovi is more common among sylvatic carnivores (89.0%), while T. spiralis prevails in wild boars (62.0%), domestic swine (82.0%) and rodents (75.0%). CONCLUSION: The results of our study represent the first molecular identification of species of the genus Trichinella in Bosnia and Herzegovina. Additionally, our findings underscore the necessity for targeted epidemiological studies to thoroughly assess trichinellosis prevalence across diverse animal populations. Considering the relatively high frequency of trichinellosis infection in investigated animal species and its public health implications, there is an evident need for establishing an effective trichinellosis surveillance system in Bosnia and Herzegovina.


Asunto(s)
Carnívoros , Enfermedades de los Gatos , Enfermedades de los Perros , Lynx , Mustelidae , Enfermedades de los Roedores , Enfermedades de los Porcinos , Trichinella , Triquinelosis , Ursidae , Lobos , Humanos , Animales , Porcinos , Perros , Gatos , Trichinella/genética , Triquinelosis/epidemiología , Triquinelosis/veterinaria , Bosnia y Herzegovina/epidemiología , Sus scrofa , Carnívoros/parasitología , Roedores , Hurones , Zorros/parasitología , Larva , Enfermedades de los Porcinos/epidemiología
3.
Diagn Microbiol Infect Dis ; 109(2): 116268, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38513559

RESUMEN

Mpox virus (MPXV) infection is difficult to distinguish from other (non-)infectious diseases. The etiology of rash can be differentiated by real-time polymerase chain reaction (rtPCR) on different types of samples. The study aims to provide experience with emerging MPXV diagnostics in a tertiary-level laboratory in Bosnia and Herzegovina. From July-December 2022, a total of 18 mpox suspected persons were tested. MPXV infection was confirmed by rtPCR in 10/18 (55.56 %) persons. The number of cases reached a peak in October 2022. The lowest median Crossing point (Cp) (x̄ = 29.76) was obtained from a swab of skin lesions in a viral transport medium (VTM). Evaluating the Cp values for the 7/9 mpox cases from whom paired swab samples from different anatomic sites were collected, higher positivity of skin lesion swabs in VTM was observed. In conclusion, our data highlighted the confirmatory role of rtPCR in the diagnosis of MPXV in skin lesion samples.


Asunto(s)
ADN Viral , Reacción en Cadena en Tiempo Real de la Polimerasa , Humanos , Bosnia y Herzegovina , Reacción en Cadena en Tiempo Real de la Polimerasa/métodos , ADN Viral/genética , ADN Viral/aislamiento & purificación , Masculino , Femenino , Adulto , Mpox/diagnóstico , Mpox/virología , Mpox/epidemiología , Persona de Mediana Edad , Adolescente , Adulto Joven , Centros de Atención Terciaria , Niño , Monkeypox virus/genética , Monkeypox virus/aislamiento & purificación , Piel/virología , Técnicas de Diagnóstico Molecular/métodos
4.
Euro Surveill ; 29(9)2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-38426241

RESUMEN

We report on an ongoing measles outbreak in the Federation of Bosnia and Herzegovina with 141 cases notified between week 52 2023 and week 6 2024. Among those with known vaccination status, 97% were unvaccinated and the most affected group is children under the age of 5 years (n = 87) who were not vaccinated during the pandemic years. Sixty-eight cases were hospitalised, the most common complications were measles-related pneumonia and diarrhoea. The sequenced measles viruses from four cases belonged to genotype D8.


Asunto(s)
Exantema , Sarampión , Niño , Humanos , Preescolar , Vacunación , Bosnia y Herzegovina/epidemiología , Sarampión/epidemiología , Sarampión/prevención & control , Virus del Sarampión/genética , Brotes de Enfermedades/prevención & control
5.
Zootaxa ; 5405(3): 422-432, 2024 Jan 31.
Artículo en Inglés | MEDLINE | ID: mdl-38480378

RESUMEN

A new subterranean leptodirine leiodid beetle, Speoplanes biocovensis bosnicus Vrbica, Vesovi, Raa & uri, ssp. n., is described and diagnosed from a pit in southern Bosnia and Herzegovina. This is the first discovery of the genus Speoplanes Mller, 1911 in this country and the first discovery outside Croatia. Important morphological features of the new taxon are presented, including aspects of the male and female genitalia. The subspecies is endemic to the Dinaric mountain range of Bosnia and Herzegovina. A key to the identification of taxa of the genus Speoplanes is added.


Asunto(s)
Escarabajos , Femenino , Masculino , Animales , Bosnia y Herzegovina , Croacia
6.
Hip Int ; 34(1): 74-81, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-37795618

RESUMEN

BACKGROUND: Despite the overall success of THA, between 5 and 20% report unsatisfactory results. Several factors may cause this variable outcome. 1 of them might be ethnicity which, because of its potential social impact on living conditions, may influence quality of life too. It should be studied whether patients born and being operated in their home country Bosnia and Herzegovina (BH) had similar results as immigrants being operated in Sweden (IS). METHODS: Data of 280 patients were collected prospectively from questionnaires in the BH group. Patients of the IS group were eligible if both of their parents were born outside the Nordic countries, not having Swedish as their native language. Data were gained from the Swedish Arthroplasty Registry (SAR), 449 patients were included. Outcomes were pain VAS, satisfaction VAS, EQ-VAS, and the EQ-5D. Logistic and linear regression models including age, sex, diagnosis, type of fixation, surgical incision, marital status and educational level were analysed to compare those 2 groups. RESULTS: There were considerable differences in patient demographics between the 2 groups. Before the operation, patients in the BH group reported more problems with self-care and usual activities, even after adjustment for confounding factors (p < 0.0005). Patients in the IS group reported a higher EQ-VAS and more pain VAS (p < 0.0005), the difference in the EQ-VAS was not significant after adjustment for confounding factors (p = 0.41). After 1 year patients in the BH group reported better scores in all dimensions of the EQ-5D (p ⩽ 0.005) apart from self-care. After adjustment for confounding factors, patients in the BH group were more satisfied too (p < 0.0005). CONCLUSIONS: Immigrated patients (IS group) seemed to experience less benefit from THA 1 year after the operation despite more symptoms preoperatively. There were considerable limitations affecting the results. Nevertheless, the data are a point of concern, and it is suggested to take more multidimensional care of immigrant patients.


Asunto(s)
Artroplastia de Reemplazo de Cadera , Emigrantes e Inmigrantes , Humanos , Artroplastia de Reemplazo de Cadera/efectos adversos , Suecia , Resultado del Tratamiento , Calidad de Vida , Bosnia y Herzegovina , Encuestas y Cuestionarios , Dolor/etiología
7.
Ther Apher Dial ; 28(3): 409-416, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38115783

RESUMEN

INTRODUCTION: Due to treatment of end-stage-renal-disease (ESRD), continuous peritoneal dialysis (CAPD) is used in 11% of cases and is associated with several PD-associated infections. METHODS: Clinical data on 71 patients with CAPD were evaluated in addition to exit site infections and episodes of acute peritonitis (AP). RESULTS: There were 39 men and 32 women. Average age was 61 years when we began CAPD and average time spent on CAPD program was 3.35 years. Illness that dominantly caused ESRD was diabetes (23 patients). Exit site infection was mostly caused by S epidermidis-MRSE and AP was most commonly caused by Staphylococcus sp. group. Most common cause of death was cardiovascular disease. At the end of this study, 9 patients were alive and still on CAPD, 10 were transplanted, 15 switched to HD and 36 died. CONCLUSION: Optimal prevention measures and treatment of infectious complications in CAPD is necessary for better treatment possibilities.


Asunto(s)
Fallo Renal Crónico , Diálisis Peritoneal Ambulatoria Continua , Peritonitis , Humanos , Masculino , Femenino , Persona de Mediana Edad , Bosnia y Herzegovina/epidemiología , Peritonitis/etiología , Peritonitis/epidemiología , Peritonitis/microbiología , Diálisis Peritoneal Ambulatoria Continua/efectos adversos , Diálisis Peritoneal Ambulatoria Continua/métodos , Fallo Renal Crónico/terapia , Anciano , Adulto , Estudios Retrospectivos , Anciano de 80 o más Años
8.
PLoS One ; 18(11): e0292730, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-38015900

RESUMEN

This study aimed to explore the experiences of older migrants' (70+) access to and participation in different meeting places. Qualitative interviews were conducted with participants originating from Finland and four countries in the Western Balkans: Bosnia- Herzegovina, Croatia, Montenegro, and Serbia. The participants used everyday places in the neighborhood, which were not primarily meant to be meeting places, to create and uphold social contacts. These meeting places contributed to experiences of community and trust. Both everyday meeting places and organized meeting places were used to establish and develop relationships that could result in an exchange of both practical and emotional support. Perceptions of "not belonging", limited proficiency in Swedish, and a strained financial situation created barriers to accessing some meeting places. The results of this study demonstrate the significance of meeting places that are not purposefully aimed at older people in general or older people from a specific country.


Asunto(s)
Migrantes , Humanos , Anciano , Serbia , Bosnia y Herzegovina , Montenegro , Servicio Social
9.
BMC Prim Care ; 24(1): 241, 2023 11 16.
Artículo en Inglés | MEDLINE | ID: mdl-37968592

RESUMEN

INTRODUCTION: The management of long-term physical conditions is a challenge worldwide, absorbing a majority resources despite the importance of acute care. The management of these conditions is done largely in primary care and so interventions to improve primary care could have an enormous impact. However, very little data exist on how to do this. Mental distress is frequently comorbid with long term physical conditions, and can impact on health behaviour and adherence, leading to poorer outcomes. DIALOG+ is a low-cost, patient-centred and solution-focused intervention, which is used in routine patient-clinician meetings and has been shown to improve outcomes in mental health care. The question arises as to whether it could also be used in primary care to improve the quality of life and mental health of patients with long-term physical conditions. This is particularly important for low- and middle-income countries with limited health care resources. METHODS: An exploratory non-controlled multi-site trial was conducted in Bosnia and Herzegovina, Colombia, and Uganda. Feasibility was determined by recruitment, retention, and session completion. Patient outcomes (quality of life, anxiety and depression symptoms, objective social situation) were assessed at baseline and after three approximately monthly DIALOG+ sessions. RESULTS: A total of 117 patients were enrolled in the study, 25 in Bosnia and Herzegovina, 32 in Colombia, and 60 in Uganda. In each country, more than 75% of anticipated participants were recruited, with retention rates over 90% and completion of the intervention exceeding 92%. Patients had significantly higher quality of life and fewer anxiety and depression symptoms at post-intervention follow-up, with moderate to large effect sizes. There were no significant improvements in objective social situation. CONCLUSION: The findings from this exploratory trial suggest that DIALOG+ is feasible in primary care settings for patients with long-term physical conditions and may substantially improve patient outcomes. Future research may test implementation and effectiveness of DIALOG+ in randomized controlled trials in wider primary care settings in low- and middle-income countries. TRIAL REGISTRATION: All studies were registered prospectively within the ISRCTN Registry. ISRCTN17003451, 02/12/2020 (Bosnia and Herzegovina), ISRCTN14018729, 01/12/2020 (Colombia) and ISRCTN50335796, 02/12/2020 (Uganda).


Asunto(s)
Atención Primaria de Salud , Calidad de Vida , Humanos , Bosnia y Herzegovina , Colombia/epidemiología , Uganda/epidemiología , Estudios de Factibilidad
11.
Environ Monit Assess ; 195(11): 1338, 2023 Oct 19.
Artículo en Inglés | MEDLINE | ID: mdl-37856003

RESUMEN

Droughts are second to hurricanes the world's most costly weather events. Damage caused by droughts in certain countries is measured in tens of billions of dollars per year. Timely detection of drought and prediction of its occurrence has the potential to reduce costs and save a large number of people from its consequences. Numerous methods that serve this purpose exist in scientific research and practice. One group of drought monitoring methods belongs to the field of remote sensing, where it is possible to monitor drought indicators over large areas in almost real-time through satellite images. This paper is focused on the optical indices of remote sensing calculated by raster algebra. The intention was to reach conclusions about the quality of individual indices used for the Canton Sarajevo area in Bosnia and Herzegovina for each month of August in the period 2008-2021 through correlational and qualitative analysis and the use of meteorological indicators. Among the used indices, NDVI (normalized difference vegetation index) and NMI (normalized moisture index) proved to be the most reliable, and their mutual correlation was very strong (r = 0.99).


Asunto(s)
Sequías , Tecnología de Sensores Remotos , Humanos , Bosnia y Herzegovina , Monitoreo del Ambiente/métodos , Meteorología
12.
Int J Public Health ; 68: 1606411, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37901591

RESUMEN

Objectives: To conduct qualitative study with different target groups in Bosnia and Herzegovina in order to explore their views on barriers and drivers for COVID-19 vaccination, and to see if and how barriers and drivers vary between urban and rural locations, and different professional roles. Methods: The theoretical framework underpinning the study is the capability-opportunity-motivation (COM-B) behavior change framework, which has been adapted to monitor vaccine related behavior and attitudes. Data was collected from June to September 2022 through moderated discussions in focus groups. The total of 162 participants participated in 16 focus groups. Results: Among the key barriers to successful immunization identified across target groups were insufficient knowledge about vaccines, pandemic fatigue, concerns about the rapid development of the vaccine and its effectiveness, lack of confidence in the healthcare system. Some of the main drivers of vaccination against COVID-19 were confidence in science and expert recommendations. Conclusion: The COVID-19 immunization policy undergoes continuous changes, as do the pandemic prospects; we encourage further research to track the evolution of vaccine related attitudes, inform immunization policy, and create evidence-based interventions.


Asunto(s)
Vacunas contra la COVID-19 , COVID-19 , Humanos , Bosnia y Herzegovina , Pandemias/prevención & control , COVID-19/epidemiología , COVID-19/prevención & control , Emociones
13.
Medicina (Kaunas) ; 59(10)2023 Sep 27.
Artículo en Inglés | MEDLINE | ID: mdl-37893450

RESUMEN

Background and Objectives: Cranial defects pose significant challenges in low and middle-income countries (LIMCs), necessitating innovative and cost-effective craniofacial reconstruction strategies. The purpose of this study was to present the Bosnia and Herzegovina model, showcasing the potential of a multidisciplinary team and 3D-based technologies, particularly PMMA implants, to address cranial defects in a resource-limited setting. Materials and Methods: An observational, non-experimental prospective investigation involved three cases of cranioplasty at the Department of Neurosurgery, Cantonal Hospital Zenica, Bosnia and Herzegovina, between 2019 and 2023. The technical process included 3D imaging and modeling with MIMICS software (version 10.01), 3D printing of the prototype, mold construction and intraoperative modification for precise implant fitting. Results: The Bosnia and Herzegovina model demonstrated successful outcomes in cranioplasty, with PMMA implants proving cost-effective and efficient in addressing cranial defects. Intraoperative modification contributed to reduced costs and potential complications, while the multidisciplinary approach and 3D-based technologies facilitated accurate reconstruction. Conclusions: The Bosnia and Herzegovina model showcases a cost-effective and efficient approach for craniofacial reconstruction in LIMICs. Collaborative efforts, 3D-based technologies, and PMMA implants contribute to successful outcomes. Further research is needed to validate sustained benefits and enhance craniofacial reconstruction strategies in resource-constrained settings.


Asunto(s)
Países en Desarrollo , Polimetil Metacrilato , Humanos , Bosnia y Herzegovina , Estudios Prospectivos , Impresión Tridimensional
14.
Acta Vet Hung ; 71(2): 65-70, 2023 10 17.
Artículo en Inglés | MEDLINE | ID: mdl-37676786

RESUMEN

Nocardia cyriacigeorgica is a well-known agent of human nocardiosis and is considered an emerging pathogen, however, its identification to the species level is complex for many clinical laboratories. Available data on the clinical significance of N. cyriacigeorgica in veterinary medicine are sparse and mainly concern isolated reports of pyogranulomatous lesions in domestic animals. We report a case of severe bovine mastitis caused by N. cyriacigeorgica that did not respond to conventional antimicrobial therapy in a small holding in Bosnia and Herzegovina. After isolation of the pathogen, further identification by routine microbiological methods was not possible. Susceptibility to antimicrobials was tested using the disc diffusion method according to published recommendations. The sample was also tested by MALDI-ToF MS with inconclusive results. In addition, 16S rRNA sequence analysis, verified by multilocus sequence analysis (MLSA) using the gyrB, 16S rRNA, secA1, and hsp65 sequences, confirmed the species N. cyriacigeorgica. To our knowledge, this is the first report of isolation of N. cyriacigeorgica from a clinical case of bovine mastitis in a European dairy farm and the first MLSA method approach to distinguish a Nocardia spp. strain isolated from animals.


Asunto(s)
Enfermedades de los Bovinos , Mastitis Bovina , Nocardia , Humanos , Bovinos , Femenino , Animales , Tipificación de Secuencias Multilocus/veterinaria , ARN Ribosómico 16S/genética , Mastitis Bovina/tratamiento farmacológico , Mastitis Bovina/microbiología , Bosnia y Herzegovina , Nocardia/genética , Enfermedades de los Bovinos/tratamiento farmacológico
15.
Radiat Prot Dosimetry ; 199(19): 2303-2310, 2023 Nov 16.
Artículo en Inglés | MEDLINE | ID: mdl-37624094

RESUMEN

Cosmic rays are the primary source of the daily exposure of aircrew and passengers to ionising radiation. This study aims to estimate the effective doses of ionising radiation for aircraft crews in Bosnia and Herzegovina by taking into consideration factors such as flight duration and altitude, as well as the geographical position of airports. The CARI-7 algorithm and neural network method were used in the analysis of data obtained from the Sarajevo International Airport. The results show that the estimated annual effective doses in 2021 range from 0.06 to 10 mSv for flights to and from Belgrade and Dubai, respectively. Both linear regression and neural network models were developed to predict the effective dose based on flight duration, average altitude, latitude and maximum altitude. The findings reveal that flight duration is the most statistically significant factor, followed by average altitude, latitude and maximum altitude.


Asunto(s)
Medicina Aeroespacial , Radiación Cósmica , Exposición Profesional , Protección Radiológica , Dosis de Radiación , Medicina Aeroespacial/métodos , Protección Radiológica/métodos , Bosnia y Herzegovina , Exposición Profesional/prevención & control , Exposición Profesional/análisis , Aeronaves , Altitud
16.
Influenza Other Respir Viruses ; 17(8): e13182, 2023 08.
Artículo en Inglés | MEDLINE | ID: mdl-37621919

RESUMEN

Background: Sarajevo Canton in the Federation of Bosnia and Herzegovina has recorded several waves of high SARS-CoV-2 transmission and has struggled to reach adequate vaccination coverage. We describe the evolution of infection- and vaccine-induced SARS-CoV-2 antibody response and persistence. Methods: We conducted repeated cross-sectional analyses of blood donors aged 18-65 years in Sarajevo Canton in November-December 2020 and 2021. We analyzed serum samples for anti-nucleocapsid (anti-N) and anti-spike (anti-S) antibodies. To assess immune durability, we conducted longitudinal analyses of seropositive participants at 6 and 12 months. Results: One thousand fifteen participants were included in Phase 1 (November-December 2020) and 1152 in Phase 2 (November-December 2021). Seroprevalence increased significantly from 19.2% (95% CI: 17.2%-21.4%) in Phase 1 to 91.6% (95% CI: 89.8%-93.1%) in Phase 2. Anti-S IgG titers were significantly higher among vaccinated (58.5%) than unvaccinated infected participants across vaccine products (p < 0.001), though highest among those who received an mRNA vaccine. At 6 months, 78/82 (95.1%) participants maintained anti-spike seropositivity; at 12 months, 58/58 (100.0%) participants were seropositive, and 33 (56.9%) had completed the primary vaccine series within 6 months. Among 11 unvaccinated participants who were not re-infected at 12 months, anti-S IgG declined from median 770.1 (IQR 615.0-1321.7) to 290.8 (IQR 175.7-400.3). Anti-N IgG antibodies waned earlier, from 35.4% seropositive at 6 months to 24.1% at 12 months. Conclusions: SARS-CoV-2 seroprevalence increased significantly over 12 months from end of 2020 to end of 2021. Although individuals with previous infection may have residual protection, COVID-19 vaccination is vital to strengthening population immunity.


Asunto(s)
Donantes de Sangre , COVID-19 , Humanos , Bosnia y Herzegovina/epidemiología , COVID-19/epidemiología , COVID-19/prevención & control , Vacunas contra la COVID-19 , Estudios Transversales , SARS-CoV-2/genética , Estudios Seroepidemiológicos , Estudios Longitudinales , Inmunoglobulina G
17.
Front Public Health ; 11: 1193281, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37457274

RESUMEN

A National Immunization Technical Advisory Group (NITAG) is a multi-disciplinary body of experts that provides evidence-based recommendations on immunizations to policy-makers to assist them in making immunization policy and program decisions. NITAGs faced challenges in making evidence-based recommendations for COVID-19 vaccines during the COVID-19 pandemic due to the new vaccine products available in a short time period and limited available data on vaccine effectiveness and vaccine safety. The authors reviewed the process used by the NITAG in the Federation of Bosnia and Herzegovina, called the expert body, to develop COVID-19 vaccine recommendations. The article reviews the evidence that was considered by the expert body when developing 23 recommendations on COVID-19 vaccination and describes the challenges and successes faced by the body. The expert body recommendations led to the successful roll-out of COVID-19 vaccines and provided guidance for COVID-19 vaccination during the pandemic. The expert body plans to improve its work and procedures for developing routine immunization recommendations with the support of the WHO Regional Office for Europe.


Asunto(s)
COVID-19 , Vacunas , Humanos , Vacunas contra la COVID-19 , Pandemias , Bosnia y Herzegovina , Política de Salud , Comités Consultivos , Programas de Inmunización , COVID-19/epidemiología , COVID-19/prevención & control , Vacunación , Inmunización
18.
Acta Med Acad ; 52(1): 13-23, 2023 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-37326393

RESUMEN

OBJECTIVES: The main objective of this paper was to examine the perceptions of family physicians on the use of primary health care in Bosnia and Herzegovina during the COVID-19 pandemic. MATERIALS AND METHODS: A cross-sectional study was conducted using a short online questionnaire that was sent to primary care physicians in Bosnia and Herzegovina from April 20th, 2022, to May 20th, 2022. RESULTS: The research sample consisted of 231 doctors of primary health care from Bosnia and Herzegovina, with an average age of 45 years and 85% women. About 70% of participants reported having COVID-19 at least once from March 2020 to March 2022. Participants had an average of 1,986 registered patients and approximately 50 encounters per day. The study revealed a high degree of reliability between test-retest measurements, with a single measure Intraclass correlation coefficient of 0.801, and internal consistency determined using Cronbach's alpha of 0.89. Participants reported that the following health services were most affected during the COVID-19 pandemic: care for patients with chronic diseases, home visits, navigating the health system with patients making appointments with specialists, cancer screening, and preventive health services. The study also found statistically significant perceived differences in the use of these health services based on age, gender, postgraduate education in family medicine, participation in COVID-19 clinics, and personal history of Covid-19. CONCLUSION: There were significant disturbances to the use of primary health care during the COVID-19 pandemic. Future research could investigate patient outcomes compared to family physician perceptions.


Asunto(s)
COVID-19 , Médicos de Familia , Humanos , Femenino , Persona de Mediana Edad , Masculino , Bosnia y Herzegovina , COVID-19/epidemiología , Estudios Transversales , Pandemias , Reproducibilidad de los Resultados , Atención Primaria de Salud
19.
Acta Med Acad ; 52(1): 1-12, 2023 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-37326392

RESUMEN

OBJECTIVE: The aim of this study was to investigate students' knowledge, attitudes and hesitancy regarding COVID-19 vaccination. METHODS: A cross-sectional questionnaire-based survey was conducted among a total of 1282 medical students and 509 non-medical students at four public universities in Bosnia and Herzegovina: Tuzla, Sarajevo, Banja Luka, and Mostar. RESULTS: A significantly higher rate of vaccination was observed in the group of medical students as well as a higher level of knowledge about vaccination in general and vaccines against the COVID-19 disease. Students who received the COVID-19 vaccine had a higher level of knowledge about vaccination in general and COVID-19 vaccines in particular compared to the non-vaccinated students in the medical and non-medical groups, respectively. Furthermore, vaccinated students, regardless of the course they are taking, showed generally stronger positive attitudes compared to non-vaccinated students, regarding the safety and effectiveness of the COVID-19 vaccine. Both groups of students believe that the rapid development of the vaccine is contributing to refusal or hesitancy to receive a vaccine against COVID-19. Social media/networks were the main sources of information about the COVID-19 vaccine. We did not find any contribution of social media to the reduced level of COVID-19 vaccine coverage. CONCLUSION: Education of students about the benefits of the COVID-19 vaccine will lead to its better acceptance as well as the development of more positive attitudes towards vaccination in general, especially having in mind that students are the future population of parents, who will make decisions about vaccinating their children.


Asunto(s)
COVID-19 , Estudiantes de Medicina , Niño , Humanos , Vacunas contra la COVID-19/uso terapéutico , Bosnia y Herzegovina , Estudios Transversales , COVID-19/prevención & control , Vacunación , Estudiantes , Actitud , Conocimientos, Actitudes y Práctica en Salud
20.
BMC Oral Health ; 23(1): 429, 2023 06 28.
Artículo en Inglés | MEDLINE | ID: mdl-37380985

RESUMEN

BACKGROUND: The clinical measures are not sufficient to assess oral health because they don't tell us anything about functional and psychosocial aspects of oral health and do not reflect person's concerns and subjectively perceived symptoms. This study aimed to investigate the validity, reliability and responsiveness of the child Oral Impacts on Daily Performances (C-OIDP) index among Bosnian 12-14 years old schoolchildren. METHODS: The study population comprised 203 primary schoolchildren aged 12-14 years attending three schools in the eastern part of Bosnia and Herzegovina. Data were collected through: a clinical oral examination, oral health questionnaire and C-OIDP questionnaire. The validity and reliability of the C-OIDP were tested on a sample of 203 school-going children while responsiveness of the C-OIDP was assessed on 42 randomly chosen participants requiring a dental treatment. RESULTS: In terms of reliability, Cronbach's alpha coefficient and the intraclass correlation coefficient were 0.86 and 0.85, respectively. Regarding the testing of construct validity, the C-OIDP score was increased as children's self-reported oral health changed from excellent to very bad and from very satisfied to dissatisfied. There was a significant improvement in C-OIDP post-treatment score compared with C-OIDP pre-treatment score. Overall, 63.4% of participants reported at least one oral impact in the last 3 months. The most affected performances were "eating" (38.4%) and "speaking" (25.1%). CONCLUSION: The Bosnian version of the C-OIDP showed satisfactory validity, reliability and responsiveness and can be used as an appropriate OHRQoL measure for further epidemiological researches.


Asunto(s)
Examen Físico , Humanos , Adolescente , Niño , Psicometría , Bosnia y Herzegovina , Estudios Transversales , Reproducibilidad de los Resultados
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA